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Viagra Linked to Aggressive Behavior and Sexual Violence

Researchers and scientists are debating whether Viagra can be linked to aggressive behavior and sexual violence — and whether it’s necessary for doctors to warn users about the potential psychological and emotional side effects.

According to a report, published in the Annals of Pharmacotherapy, 270 adverse reaction reports had been collected and archived by the U.S. Food and Drug Administration (FDA).

The 270 reports detailed a variety of the side effects associated with Viagra — including dizziness, disorientation, and amnesia.

According to the report, Viagra was also suspect in 22 reports involving aggression, 13 involving rape, and six involving murder.

Despite it’s potential link to aggressive behavior and sexual violence, FDA officials have no plans to change Viagra’s label.

Viagra’s manufacturer, Pfizer Inc., claim this report is unsound.

The report was compiled by Dr. Harold A.Milman, a toxicologist based in Rockville, MD, who has also served as a senior advisor at the U.S. Environmental Protection Agency for 18 years, as well as a cancer-drug expert at the National Institutes of Health for 10 years.

“I’m not saying Viagra causes anything, but there is evidence to suggest an association.” Milman acknowledged adverse-event reports are anecdotal evidence, but said, “it’s clear these men are behaving abnormally.”

Adverse-event reports are often used as a way to flag side effects in the general population that may have been missed during clinical studies.

Research was cited in Milman’s report, showing that Viagra (Sildenafil) can enter the brain and that the drug could potentially affect biological pathways in parts of the brain that control sexual responses and aggression.

SOURCE: Annals of Pharmacotherapy, July 2002; Reuters Health, December 6, 2002, www.reuters.com.